A new University of California-Riverside study has just identified alternate chemistry that could cause the various pathologies associated with Alzheimer’s.
Up until now, researchers have focused on plaques and tangles, with the dominant theory that buildup over time causes the disease. But scientists have attempted dozens of clinical trials on that theory, and they’ve all failed, says Ryan R. Julian, the new study’s lead.
The UCR study reveals that lysosomal storage is a “likely cause of Alzheimer’s.” Fragile neurons that don’t undergo cell division are especially vulnerable to lysosomal problems.
Long-lived proteins become harder to come by as we age.