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Weight gain: new brain-gut connection revealed

Weight gain: new brain-gut connection revealed

Photo: jarmoluk/Pixabay

Researchers at Baylor College of Medicine uncovered exactly how eating extra food leads to obesity: there’s a brain-gut connection.

The hormone leptin, produced by fat cells, is critical to controlling body weight. It triggers a full sensation in the brain when we’ve eaten enough and should stop.

But if we overeat or eat a high-fat diet, the body stops responding to leptin signals and doesn’t trigger that full message. So we continue eating.

“We have uncovered a new piece of the complex puzzle of how the body manages energy balance and affects weight,” said Dr. Makoto Fukuda.

The Baylor researchers hope their findings will evolve into weight-loss strategies that can restore the brain’s ability to respond to leptin.

More at Science Daily

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