Researchers at Baylor College of Medicine uncovered exactly how eating extra food leads to obesity: there’s a brain-gut connection.
The hormone leptin, produced by fat cells, is critical to controlling body weight. It triggers a full sensation in the brain when we’ve eaten enough and should stop.
But if we overeat or eat a high-fat diet, the body stops responding to leptin signals and doesn’t trigger that full message. So we continue eating.
“We have uncovered a new piece of the complex puzzle of how the body manages energy balance and affects weight,” said Dr. Makoto Fukuda.
The Baylor researchers hope their findings will evolve into weight-loss strategies that can restore the brain’s ability to respond to leptin.